Watter aluminiumlegering is geskik vir mediese blisterfoelie?

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Watter aluminiumlegering is geskik vir mediese blisterfoelie?

Blister foelie, Ook bekend as PTP aluminiumfoelie (Druk deur pakket aluminiumfoelie) of aluminium-plastiek blisterverpakkingsmateriaal op die gebied van farmaseutiese verpakking, is a major form of pharmaceutical packaging.

Blister foil is mainly made of electrolytic aluminum calendering, with good ductility and uniform thinness, usually less than 0.2mm thick. It is mainly used for heat sealing with transparent plastic hard sheets (such as PVC, PVDC-coated PVC, PP, ens.) to form blister packaging.

The raw material manufacturing of blister foil generally uses aluminum foil alloy. The aluminum alloy used for medical blister foil is specially selected to protect the encapsulated drugs from external factors (soos vog, lig en suurstof), because these factors will reduce the effectiveness of the drug. The most commonly used aluminum alloy is 8011-H18.

Here is a detailed description of 8011-H18 for medical blister foil:

8011-H18 Aluminum Alloy

1. Samestelling:

Aluminum content: na beraming 98%, with the remaining 2% consisting of elements such as iron and silicon. These small amounts of additional elements provide the necessary strength and workability without compromising the alloy’s protective properties.

2. Mechanical Properties:

Ultimate Tensile Strength: 125 – 165 MPa.

– Lewer krag: 110 – 145 MPa.

– Verlenging: Typically less than 3%.

H18 temper means the foil is completely hard with excellent stiffness and resistance to deformation. This is critical for blister packaging to maintain the integrity of the package, especially during the sealing process.

3. Versperringseienskappe:

Excellent Moisture Barrier: 8011-H18 foil has excellent moisture barrier properties, which is critical for protecting sensitive medications from moisture.

– Ligte versperring: Aluminum foil provides 100% versperring vir lig, which can degrade light-sensitive medications.
– Suurstofversperring: It effectively prevents oxygen penetration, ensuring the shelf life of oxygen-sensitive products.
– Chemiese weerstand: The alloy is resistant to many chemicals, helping to protect medications from potential contamination.

4. Processability and Sealability:

Vormbaarheid: Although aluminum foil is very hard (H18), it is still malleable enough to be formed into blister packs, which typically require complex forming.

Hitte seëlbaarheid: 8011-H18 aluminum foil is compatible with a variety of heat-sealable coatings, so it can be effectively sealed to a variety of substrates, such as PVC (polivinielchloried) of pvdc (polivinielideenchloried) commonly used in blister packs.

5. Dikte:
– Tipies, aluminum foil used in blister packs is 20 aan 25 mikron dik, which provides the necessary barrier but is thin enough for patients to easily pierce the foil to access medication.

6. Other considerations:
Cost-effectiveness: 8011-H18 aluminum foil is relatively cost-effective, balancing the need for high-quality protection with manufacturing efficiency.
– Drukbaarheid: The surface of 8011-H18 aluminum foil can be easily printed, which is important for printing product information, branding and safety warnings directly on the packaging.

8011-H18 aluminum alloy is the material of choice for medical blister foil due to its excellent barrier properties, mechanical strength and compatibility with pharmaceutical regulations. Alumni foil 8011 ensures that drugs remain safe, effective and easily accessible to patients throughout their shelf life.

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